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Beilstein J. Org. Chem. 2021, 17, 229–233, doi:10.3762/bjoc.17.23
Graphical Abstract
Scheme 1: Electrophilic decarboxylative functionalization of 2-pyridylacetates.
Scheme 2: One-pot procedure for the synthesis of 2a.
Scheme 3: Substrate scope. aSaponification was carried out with 2.5 equiv of LiOH, and 2.5 equiv of 6 was use...
Scheme 4: Reaction of α-monosubstituted 2-pyridylacetates.
Scheme 5: Proposed reaction pathway.
Scheme 6: Reaction of 3- and 4-pyridylacetates.